Endocarditis- Algorithms

Daniel J Weber, Tobias Deuse

Modified Duke’s Criteria:

  • Need 2 major, 1 major + 3 minor, or 5 minor criteria

Major criteria:

  • Typical organisms from two separate cultures >12 hrs apart
  • Endocardial involvement on Echo
  • Single Coxiella culture or IgG positive titer

Minor Criteria:

  • IV drug use or predisposing heart condition
  • Temp > 38
  • Vascular phenomenon
  • Immunologic phenomenon

Objectives of Surgical Management:

  • Remove infected tissues
  • Restore hemodynamics and valvular architecture
  • Prevent embolic events
  • Open/explore right atrium for those with conduction deficits
  • NVE requires at least 6 weeks of post-op antimicrobial therapy
  • PVE generally requires at least 8 weeks of antimicrobial therapy
  • Complete removal of Pacemaker/Defibrillator system for documented infection of device or leads
  • Complete removal of Pacemaker/Defibrillator system reasonable with endocarditis caused by staph aureus or fungi

AI, aortic insufficiency; HACEK, haemophilus, actinobacillus, cardiobacterium, eikenella, kingella; MDR, multi-drug resistant; MR, mitral regurgitation; NVE, native valve endocarditis; PVE, prosthetic valve endocarditis; PVL, paravalvular leak; TEE, transesophageal echocardiography

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